A dental implant is a biocompatible surgical component placed into the jawbone to support dental prosthesis including bridges, crowns, or denture replacements. Currently, dental implants are constructed employing solid materials, coated with biocompatible layers. Since bone is a living tissue that is constantly modified in response to external loading, redistributed mechanical loading might cause bone resorption and interface failure, all of which have been notable problems for orthopedic implants. To overcome these issues, we propose a new design for the dental implant structure that can simultaneously minimize bone loss and interface failure. Multiscale and multi-objective design optimization of dental implants employing lattice materials were performed by considering lattice structure in implant design. The proposed design was capable of reducing simultaneously the interface failure and bone loss, as well as implant weight