In this study, the potential benefits of retrofitting concrete bridges with self-centering energy-dissipation (SCED) braces are investigated. For this purpose, four concrete bridges with pre-stressed decks are selected as study cases. Three-dimensional nonlinear models of these bridges are analyzed using OpenSEES. Nonlinear time-history analyses are conducted to evaluate the seismic performance of the original and retrofitted bridge structures. These models are subjected to earthquake records at maximum credible hazard level. A design procedure for the SCED braces is proposed. The target activation force design factor DF and the energy dissipation capacity β are the two major design parameters investigated in the parametric study and the combination of design parameter is recommended based on the bridge geometry and brace configuration. The results demonstrate that the SCED brace system improves the seismic performance of all example bridges by decreasing peak drifts and eliminating residual displacements during and after the seismic events.