Testing Natural Products for Toxicity against Agricultural Pests and Pathogens
Public Deposited- Resource Type
- Creator
- Abstract
In a constant race to overcome pesticide resistance by pests and pathogens, this research aimed to discover bioactive inhibitory compounds from natural products. I tested extracts from 10 different fungal isolates that were previously shown to have antifungal activity, and 5 commercially available natural products. Assays were developed to test natural products for antibiotic activities against model pathogens and pests including fungi, insects, and molluscs. The objectives of this research were to develop and determine the effectiveness of bioassays, and to identify potentially interesting natural products. Of the 10 fungal isolates tested, reconstituted broths ofPenicillium virgatum,Ramularia vizellae, andTrichodermasp. showed pronounced anti-fungal activity. Further,P. virgatumandTrichodermasp. shows anti-insect activity while broths ofRamularia vizellaeandTrichodermasp. exhibited anti-mollusc activity. A preliminary metabolomic study identified potentially interesting metabolites that requires further investigation to determine the chemical structure(s), mode of action, and other attributes.
- Subject
- Language
- Publisher
- Thesis Degree Level
- Thesis Degree Name
- Thesis Degree Discipline
- Identifier
- Rights Notes
Copyright © 2019 the author(s). Theses may be used for non-commercial research, educational, or related academic purposes only. Such uses include personal study, research, scholarship, and teaching. Theses may only be shared by linking to Carleton University Institutional Repository and no part may be used without proper attribution to the author. No part may be used for commercial purposes directly or indirectly via a for-profit platform; no adaptation or derivative works are permitted without consent from the copyright owner.
- Date Created
- 2019
Relations
- In Collection:
Items
Thumbnail | Title | Date Uploaded | Visibility | Actions |
---|---|---|---|---|
haider-testingnaturalproductsfortoxicityagainstagricultural.pdf | 2023-05-05 | Public | Download |