Active and Multi-View Machine Learning for microRNA Prediction
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This thesis explores two emerging trends in semi-supervised machine learning to maximize the utility of both labelled and unlabelled training data. Specifically, this thesis explores the application of active learning and multi-view co-training to microRNA prediction for the first time. Results show that our active learning approach is able to greatly improve classification performance using a small number of labeled instances, outperforming state-of-the-art methods under equivalent training data constraints. Multi-view co-training results also demonstrate improved performance compared to single view classifiers and yield high classification performance using a minimum number of labeled instances for classification. This thesis demonstrates that semi-supervised machine learning is likely to be useful in creating predictors of novel miRNA, particularly for species where few training exemplars are available.
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Copyright © 2018 the author(s). Theses may be used for non-commercial research, educational, or related academic purposes only. Such uses include personal study, research, scholarship, and teaching. Theses may only be shared by linking to Carleton University Institutional Repository and no part may be used without proper attribution to the author. No part may be used for commercial purposes directly or indirectly via a for-profit platform; no adaptation or derivative works are permitted without consent from the copyright owner.
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- 2018
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sheikhhassani-activeandmultiviewmachinelearningformicrorna.pdf | 2023-05-05 | Public | Download |