Active and Multi-View Machine Learning for microRNA Prediction

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Creator: 

Sheikh Hassani, Mohsen

Date: 

2018

Abstract: 

This thesis explores two emerging trends in semi-supervised machine learning to maximize the utility of both labelled and unlabelled training data. Specifically, this thesis explores the application of active learning and multi-view co-training to microRNA prediction for the first time. Results show that our active learning approach is able to greatly improve classification performance using a small number of labeled instances, outperforming state-of-the-art methods under equivalent training data constraints. Multi-view co-training results also demonstrate improved performance compared to single view classifiers and yield high classification performance using a minimum number of labeled instances for classification. This thesis demonstrates that semi-supervised machine learning is likely to be useful in creating predictors of novel miRNA, particularly for species where few training exemplars are available.

Subject: 

Engineering - Biomedical

Language: 

English

Publisher: 

Carleton University

Thesis Degree Name: 

Master of Applied Science: 
M.App.Sc.

Thesis Degree Level: 

Master's

Thesis Degree Discipline: 

Engineering, Biomedical

Parent Collection: 

Theses and Dissertations

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