Kinetic effect of some straight chain aliphatic amines on yeast alcohol dehydrogenase
Public Deposited- Resource Type
- Creator
- Abstract
Initial rate studies of the forward reaction, for Yeast Alcohol Dehydrogenase, were carried out with varying concentration of several straight chain aliphatic monoamines and diamines over the pH range from 8.0 to 10.5. Aliphatic amines appear to either activate or inhibit Yeast Alcohol Dehydrogenase for a pH less than or greater than 9.5 respectively. The concentration of the amine enhances the observed activation or inhibition. The rotonated amine activates while the nonprotonated amine inhibits the enzyme. When both amine species are present in solution the observed effect will depend on the magnitude of the two opposing reactions. The rotonated amine acts as a modifier for the enzyme while the nonprotonated amine competes with B-nicotinamide adenine dinucleotide for the coenzyme active site. All data were treated by a weighted least squares method.
- Subject
- Language
- Publisher
- Thesis Degree Level
- Thesis Degree Name
- Thesis Degree Discipline
- Identifier
- Access Rights
This work is available on request. You can request a copy at https://library.carleton.ca/forms/request-pdf-copy-thesis
- Rights Notes
Copyright © 1975 the author(s). Theses may be used for non-commercial research, educational, or related academic purposes only. Such uses include personal study, research, scholarship, and teaching. Theses may only be shared by linking to Carleton University Institutional Repository and no part may be used without proper attribution to the author. No part may be used for commercial purposes directly or indirectly via a for-profit platform; no adaptation or derivative works are permitted without consent from the copyright owner.
- Date Created
- 1975
Relations
- In Collection: