Model studies for the total synthesis of camptothecin

Creator: 

Chen, Lu-yu

Date: 

1970

Abstract: 

The work in this thesis consists of a study of some reactions related to approaches possible to the total synthesis of camptothecin (I), namely (a) modified Friedlander condensation and (b) decarboxylation studies for the ABC system plus (c) alkylation and (d) deketalization studies aimed at a CDE ring system.

A fold out sheet at the end of the thesis contains structures of the important compounds mentioned in this thesis.

Subject: 

Camptothecin
Ring Formation (Chemistry)

Language: 

English

Publisher: 

Carleton University

Thesis Degree Name: 

Master of Science: 
M.Sc.

Thesis Degree Level: 

Master's

Thesis Degree Discipline: 

Chemistry

Parent Collection: 

Theses and Dissertations

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