Laser Induced Neuro-Stimulation Analysis for Potential Treatment of Post-Traumatic Stress Disorder

Patients suffering from Post-Traumatic Stress Disorder (PTSD), often experience reduced adenosine triphosphate (ATP) production which leads to decreased neurotransmission ability. The focus of this dissertation is to establish the correlation between the photosensitivity of ATP release and (PTSD). The aim is to exploit the effectiveness of neuro-stimulation to yield higher ATP levels in cells and tissues when induced with a near infrared laser (808 nm). This is addressed by examining the transmittance of light through a variety of transcranial samples obtained from animal models. The study also highlights the comparative analysis of the efficacy of high power laser light on the viability and ATP productivity in neuroblastoma cells (SH-SY-5Y) versus cortical neurons (M-CX-400).