An Integrated Machine Learning Approach to Optimize the Estimation of Preterm Birth

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Creator: 

Ong, Daphne Eu-Jhia

Date: 

2015

Abstract: 

This thesis describes a new methodology used in conjunction with artificial intelligence tools to create multiple models for prediction of preterm birth in obstetrical environments. The data mining approach integrates: Decision Trees (DTs), Artificial Neural Networks (ANNs) - specifically a Feed Forward Back Propagation ANN, and Case Based Reasoning System (CBRS).

This work also introduces a 5by2 cross validation method, assesses two methods of attribute selection, and considers data prevalence (15% and 8.1%) in training and testing networks. Two databases were assessed from two countries: BORN (Canada) and PRAMS (USA).

Best BORN results used selection method 2, had sensitivities of 50.53%, 53.96%, specificities of 91.61%, 95.40%, and area under curves (AUC) of 0.7721, 0.7970 for Parous and Nulliparous cases respectively. Best PRAMS results used selection method 1, had sensitivities of 68.15%, 40.35%, specificities of 64.71%, 94.57%, and area under curves (AUC) of 0.8452, 0.7064 for Parous and Nulliparous cases respectively.

Subject: 

Engineering - Biomedical

Language: 

English

Publisher: 

Carleton University

Thesis Degree Name: 

Master of Applied Science: 
M.App.Sc.

Thesis Degree Level: 

Master's

Thesis Degree Discipline: 

Engineering, Biomedical

Parent Collection: 

Theses and Dissertations

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